It's not a driver or hardware issue. I've checked my RAM, I've defragmented the HD Lotro is on, I've checked the HD for errors. The game crashes every 10-20 load screens/zone changes. More so when entering highly populated zones like Galtrev. This screams memory leak to me.
This is unrelated to the frequent crashes in ROI zones/instances. Those I've been able to eliminate by muting ingame sounds. Not optimal, but at least I can play.